Journal of Medicinal and Pharmaceutical Chemistry Research

Systematic review and meta-analysis of narcolepsy management during the covid-19 pandemic

Mansour Deylami; Majid Vatankhah; Tayyebeh Zarei; Ehsan Rahmanian; Farshid Javdani; Shahram Shafa; Hasan Zabetian; Minou Najar Nobari; Kaveh Hedayati Emami; Fatemeh Maleki; Amin Shafiei; Vida Hafezi; Roohie Farzaneh; Mohammad Sadegh Sanie Jahromi

Volume 6, Issue 3 , March 2024, , Pages 292-301

https://doi.org/10.48309/jmpcr.2024.424911.1034

Abstract

The concern has recently been raised for disease status and management of people with narcolepsy after initiation of COVID-19 pandemic. Here, we evaluated the literature to determine ... Read More

Prognostic value of lymphocytes counts, serum CRP levels, and lung CT scan findings and the final disease outcome in COVID-19

Zohreh Azarkar; Ali Mohammad Zadeh; Roohie Farzaneh; Mahdi Foroughian; Behrang Rezvani Kakhki; Maryam Sobhani; Molood Fogerdi; Maryam Ziyaei; Fatemeh Maleki

Volume 6, Issue 3 , March 2024, , Pages 334-343

https://doi.org/10.48309/jmpcr.2024.425556.1036

Abstract

Introduction: Understanding the interplay of paraclinical factors in individuals with COVID-19 is crucial for predicting disease prognosis. This study aims to explore the correlation ... Read More Introduction: Understanding the interplay of paraclinical factors in individuals with COVID-19 is crucial for predicting disease prognosis. This study aims to explore the correlation between lymphocyte count, C-reactive protein (CRP) serum levels, CT scan findings, and the ultimate outcome in patients with COVID-19 pneumonia at Valiasr Hospital in Birjand.Methods: Conducting a retrospective analysis, this study investigated 258 COVID-19 patients aged 14 and above, who sought medical attention at Valiasr Hospital in Birjand city in 2020. The research meticulously documented patients' demographic details encompassing gender, age, education level, underlying health conditions, lymphocyte count, and other pertinent information. CT scan findings, the ultimate patient outcomes, and serum levels of CRP were systematically recorded and comprehensively analyzed using a study checklist. This comprehensive examination aims to provide a detailed retrospective understanding of the multifaceted factors influencing COVID-19 outcomes among patients in Birjand.Findings: The average age was 61.06±20.06 years. 50.8% of patients were male. 10.9% of patients died. The average number of lymphocytes did not differ significantly according to the severity of lung involvement (P=0.291), but the average number of WBC (P=0.031), the percentage of lymphocytes (P=0.047) and CRP (P<0.001) was significantly different from each other according to the severity of the conflict. CRP levels in discharged group were significantly lower than dead, ward and ICU admitted ones (P<0.05). CRP levels were significantly lower in without lung involvement patients than all other groups except the mild involvement group (P<0.05).Conclusion: Elevated serum levels of CRP and white blood cell count, coupled with a decrease in lymphocyte percentage, were linked to more lung involvement. Furthermore, a reduction in both the number and percentage of lymphocytes correlated with a more severe condition as well as the high CRP levels’ effect.

Investigating the difference of negative pressure in tracheal and esophageal intubation immediately after the end of cardiopulmonary resuscitation in patients referred to the emergency room

Arman Hakemi; Sahar Nosrati; Seyed Reza Habibzadeh; Majid Khadem Rezaiyan; Maryam Ziyaei; Roohie Farzaneh; Fatemeh Maleki; Mahdi Foroughian

Volume 6, Issue 1 , January 2024, , Pages 82-88

https://doi.org/10.48309/jmpcr.2024.421384.1022

Abstract

This study aimed to determine and compare the negative pressure in tracheal and esophageal intubation in the corpses immediately after the end of cardiopulmonary resuscitation. The ... Read More

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Author = Farzaneh, Roohie

Systematic review and meta-analysis of narcolepsy management during the covid-19 pandemic

Abstract

Prognostic value of lymphocytes counts, serum CRP levels, and lung CT scan findings and the final disease outcome in COVID-19

Abstract

Investigating the difference of negative pressure in tracheal and esophageal intubation immediately after the end of cardiopulmonary resuscitation in patients referred to the emergency room

Abstract